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Review

Cerebral hypoperfusion in autism spectrum disorder

Cerebral hypoperfusion, or insufficient blood flow in the brain, occurs in many areas of the brain in patients diagnosed with autism spectrum disorder (ASD). Hypoperfusion was demonstrated in the brains of individuals with ASD when compared to normal healthy control brains either using positron emission tomography (PET) or single-photon emission computed tomography (SPECT). The affected areas include, but are not limited to the: prefrontal, frontal, temporal, occipital, and parietal cortices

Geir Bjørklund, Janet K. Kern, Mauricio A. Urbina, Khaled Saad, Amira A. El-Houfey, David A. Geier, Salvatore Chirumbolo, Mark R. Geier, Jyutika A. Mehta, Jan Aaseth

Acta Neurobiologiae Experimentalis , ISSUE 1, 21–29

Review Paper

Presurgical diagnosis of epilepsies – concepts and diagnostic tools

zones are characterized. The epileptogenic lesion, the “eloquent cortex” and secondary epileptogenesis (mirror focus) are dealt with. The current diagnostic techniques used in the definition of these cortical zones, such as video-EEG monitoring, non-invasive and invasive EEG recording techniques, magnetic resonance imaging, ictal single photon emission computed tomography, and positron emission tomography, are discussed and illustrated. Potential modern surrogate markers of

Heinz Gregor Wieser

Journal of Epileptology , ISSUE 2, 115–140

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