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  • Acta Neurobiologiae Experimentalis

 

Review | 06-February-2018

Nigrostriatal interaction in the aging brain: new therapeutic target for Parkinson’s disease

striatum. Newly discovered striatal neurogenesis – normally a lifelong process – determines the efficiency of nigrostriatal interaction. Deficient neurogenesis within the striatum followed by a decline in the GABAergic/dopaminergic interaction results in progressive disconnection of the dopaminergic input, which initiates a ‘vicious circle’ cascade of neuronal damage. Effects of both deficient striatal neurogenesis and age-related neurodegeneration within the striatum accumulate, resulting in a

Janusz W. Błaszczyk

Acta Neurobiologiae Experimentalis, Volume 77 , ISSUE 1, 106–112

Original Paper | 10-December-2018

A Novel Approach to Study the Effect of Ciprofloxacin on Biofilms of Corynebacterium spp. Using Confocal Laser Scanning Microscopy

Abstract Non-diphtherial corynebacteria are Gram-positive rods that cause opportunistic infections, what is supported by their ability to produce biofilm on artificial surfaces. In this study, the characteristic of the biofilm produced on vascular and urological catheters was determined using a confocal microscopy for the most frequently involved in infections diphtheroid species. They were represented by the reference strains of Corynebacterium striatum ATCC 6940 and C. amycolatum ATCC 700207

ALINA OLENDER, AGNIESZKA BOGUT, AGNIESZKA MAGRYŚ, KATARZYNA KRÓL-TURMIŃSKA

Polish Journal of Microbiology, Volume 67 , ISSUE 4, 431–440

research-article | 06-April-2020

Local field potential power spectra and locomotor activity following treatment with pseudoephedrine in mice

, 1981). In contrast, morphine causes somnolence-like depressive activity (Wiffen et al., 2014) but also exhibits locomotor activity, as an excitatory effect (Babbini and Davis, 1972), indicating that morphine activates relatively direct CNS mechanisms, rather than enhancing cortical hyperexcitability or alertness, to increase locomotor activity. Moreover, morphine is an opioid that affects the electrical activities of the nucleus accumbens and striatum and increases movement in mice (Reakkamnuan et

Nusaib Sa-ih, Chayaporn Reakkamnuan, Nifareeda Samerphob, Dania Cheaha, Saree Niyomdecha, Ekkasit Kumarnsit

Acta Neurobiologiae Experimentalis, Volume 80 , ISSUE 1, 19–31

Research paper | 10-October-2018

Effects of extensive amygdaloid lesions on conditioned taste aversion in rats

acquisition of CTA, as has been reported with selective lesions of the basolateral amygdala. The magnitude of the taste aversion of animals with extensive lesions of the amygdala was compared with those of animals with similar lesions of the striatum (a structure apparently unrelated to CTA) and animals without lesions. Taste aversion was analyzed by the one-bottle test and two-bottle choice test. The results of the one-bottle test indicated that amygdaloid lesions significantly reduced the magnitude of

Andrés Molero-Chamizo

Acta Neurobiologiae Experimentalis, Volume 78 , ISSUE 3, 242–250

Research paper | 06-February-2018

Potential role of dopamine transporter in behavioral flexibility

Behavioral flexibility is subserved by the prefrontal cortex and the basal ganglia. Orbitofrontal cortex (OFC) and dorsomedial striatum (DMS) form a functional frontocorticostriatal circuit crucial for the mediation of flexibility during reversal learning via dopamine (DA) neurotransmission. The regulatory control in maintaining DA homeostasis and function is provided by the dopamine transporter (DAT), which therefore likely plays a significant role in controlling the influence of DA on

Anita Cybulska-Klosowicz, Julia Dabrowska, Sebastian Niedzielec, Renata Zakrzewska, Aleksandra Rozycka

Acta Neurobiologiae Experimentalis, Volume 77 , ISSUE 2, 176–189

Research paper | 22-August-2018

Changes in neurogenesis with post-hatching age in the male Japanese quail (Cortunix japonica) brain

cerebellum. Fewer PCNA-ir cells were also observed in the hypothalamus, thalamus and bed nucleus of the stria terminalis. In telencephalic ventricular zones, PCNA-ir cells were concentrated ventrally and dorsally adjacent to the mesopallium and medial striatum, respectively. DCX-ir cells were observed in the olfactory bulb, telencephalon and cerebellum. Furthermore, DCX-ir cells were scattered throughout the pallium except in the entopallium and arcopallium, septal nuclei and striatum. Fewer DCX-ir cells

Pilani Nkomozepi, Pedzisai Mazengenya, Amadi O. Ihunwo

Acta Neurobiologiae Experimentalis, Volume 78 , ISSUE 2, 173–186

Research paper | 18-May-2018

Possible role of hippocampal GPR55 in spatial learning and memory in rats

Endocannabinoids (eCBs) are involved in the hippocampal mechanisms of spatial learning and memory in rats. Although eCBs exert many of their actions on spatial learning and memory via CB1 receptors, the putative cannabinoid receptor GPR55 (expressed in the hippocampus, cortex, forebrain, cerebellum and striatum) seems to be also involved. To investigate the potential role of GPR55 in spatial learning and memory, Wistar rats received bilateral infusions of lysophosphatidylinositol (LPI, GPR55

Bruno A. Marichal-Cancino, Alfonso Fajardo-Valdez, Alejandra E. Ruiz-Contreras, Mónica Méndez-Díaz, Oscar Prospéro-García

Acta Neurobiologiae Experimentalis, Volume 78 , ISSUE 1, 41–50

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