Mini Review | 30-March-2017
It is estimated that one third of the world’s population have latent tuberculosis infection and that this is a significant reservoir for future tuberculosis cases. Most cases occur within two years following initial infection. The identification of individuals with latent tuberculosis infection is difficult due to the lack of an ideal diagnostic assay and incomplete understanding of latent infection. Currently, there are three tests: the oldest tuberculin skin test, T-SPOT.TB and the
Dagmara I. Borkowska,
Agnieszka M. Napiórkowska,
Sylwia A. Brzezińska,
Monika Kozińska,
Anna T. Zabost,
Ewa M. Augustynowicz-Kopeć
Polish Journal of Microbiology, Volume 66 , ISSUE 1, 5–8
original-paper | 06-December-2021
DAGMARA BORKOWSKA-TATAR,
MARIA KRASIŃSKA,
EWA AUGUSTYNOWICZ-KOPEĆ
Polish Journal of Microbiology, Volume 70 , ISSUE 4, 461–468
original-paper | 27-March-2019
).
The superiority of IGRAs over tuberculin skin test (TST) in LTBI diagnostic pathway, is related to its higher specificity, e.g. lack of false positive results in the populations vaccinated against M. tuberculosis and those infected with most of non-tuberculous mycobacteria (NTM) (Demkow 2011; Kuś et al. 2011; Mancuso et al. 2012). Nevertheless, some NTM, such as Mycobacterium kansasii, Mycobacterium marinum and Mycobacterium szulgai share RD1 with M. tuberculosis and could induce false positive
EWA AUGUSTYNOWICZ-KOPEĆ,
IZABELA SIEMION-SZCZEŚNIAK,
ANNA ZABOST,
DOROTA WYROSTKIEWICZ,
DOROTA FILIPCZAK,
KARINA ONISZH,
DARIUSZ GAWRYLUK,
ELŻBIETA RADZIKOWSKA,
DAMIAN KORZYBSKI,
MONIKA SZTURMOWICZ
Polish Journal of Microbiology, Volume 68 , ISSUE 1, 15–19